Audible Audio Edition
Listening Length: 1 hour and 44 minutes
Program Type: Audiobook
Version: Unabridged
Publisher: Simon & Schuster Audio / TED
Audible.com Release Date: October 13, 2015
Whispersync for Voice: Ready
Language: English
ASIN: B015RKDBKI
Best Sellers Rank: #16 in Books > Medical Books > Medicine > Medical Ethics #34 in Books > Politics & Social Sciences > Sociology > Medicine #55 in Books > Medical Books > Medicine > Diagnosis
Dr. Siddhartha Mukherjee is a brilliant oncologist whose book, "The Emperor of All Maladies: A Biography of Cancer," won the Pulitzer Prize for nonfiction. In this slim volume, the author discusses what he considers to be the essential principles of medicine: 1. A strong intuition is much more powerful than a weak test. 2. "Normals" teach us rules; "outliers" teach us laws. 3. "For every perfect medical experiment, there is a perfect human bias."Dr. Mukherjee believes that having information at your fingertips is useless unless it is paired with "clinical wisdom." To help his students, he has developed "guiding rules that a young doctor might teach himself as he navigates a profession that seems, at first glance, overwhelming unnavigable." The author presents interesting anecdotes, not just from his practice but also from the history of astronomy, citing how scientific opinions about planetary motion evolved over time. In addition, he quotes the work of Lewis Thomas and explores the ideas of Thomas Bayes, an early eighteenth century clergyman and philosopher. Mukherjee, a cogent, persuasive, and thought-provoking writer, insists that modern medicine is not an exact science. A competent physician must pay close attention to a patient's appearance, speech, and of course, his family and medical history. In addition, a proficient doctor draws on extensive experience, the laws of probability, and his "gut instinct" to solve medical mysteries. When a patient is ill, but conventional testing does not reveal the cause, savvy practitioners will look for subtle clues to assist them in making the correct diagnosis."The Laws of Medicine" is an entertaining, enlightening, and provocative look at how imagination, creativity, and medicine converge.
I bought this book immediately after the interview with Eric Topol. I had loved the Emperor of all Maladies and bought copies, hardcover, for friends and family. For a non oncologist physician and a lover of history, retired, the history of the war on cancer and the complex new genetics applications were wonderful. I had hoped this book would be the same. Isn't . I read House Of God, briefly mentioned in book and interview, when it was published. Had hoped the Laws would discuss those laws as well as ones newly formulated. I too read Lewis Thomas and Osler trying to understand medicine as a science and an art.I join with the critic who noted cost is outlandish for a tiny book filled with blank pages. TED talks are regularly pleasing, but in their brevity leave the listener eager to read more or think harder. Perhaps the book can do same, but looking at the conclusions makes me wonder if a medical student can learn.Bytes theorem is a magnificent application of an old theory, one where the mathematical statistics have been replaced by its function on common sense rules. Would that we could apply decision making to the complex formula or easily recognize when tests are not valuable, such as PSA or mammograms. Statistics in medicine are often bad statistics or unusable ones. Outcome studies require sufficient numbers to have power and so often there are more variables which may impact outcomes that are not able to be evaluated. Informed decision making is difficult.So it is with insight. The cognitive scientists and psychologists as well as philosophers have rediscovered David Hume where his idea of reason being led by passion helps us understand why groups or tribes or clans defy pure reason and act poorly.
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