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The Cell Game: Sam Waksal's Fast Money And False Promises--and The Fate Of ImClone's Cancer Drug
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Before ImClone became the stuff of the weekly newsmagazines, it was the name of a promising biotech company headed by a charming scientist named Sam Waksal, who claimed he had a "breakthrough" drug for cancer..

Hardcover: 432 pages

Publisher: HarperBusiness; 1st Printing edition edition (January 20, 2004)

Language: English

ISBN-10: 0060555564

ISBN-13: 978-0060555566

Product Dimensions: 6 x 1.3 x 9 inches

Shipping Weight: 1.5 pounds

Average Customer Review: 4.6 out of 5 stars  See all reviews (7 customer reviews)

Best Sellers Rank: #1,047,667 in Books (See Top 100 in Books) #26 in Books > Medical Books > Pharmacology > Product Development #1478 in Books > Business & Money > Business Culture > Ethics #2789 in Books > Biographies & Memoirs > Professionals & Academics > Business

This is about the Cancer Game, which might be seen as a part of the Cancer Industry, a kind of bizarre and ghoulish phenomenon of modern times that exists precisely because there is no cure for cancer. Indeed, Alex Prud'homme, who is a gifted researcher and prose stylist, whose work has appeared in such prestigious journals as The New Yorker, Vanity Fair, The New York Times, etc., might very well have called his book "The Cancer Game." I wonder why he didn't. Would such a title have offended those who play the game?It is specifically about the rise and fall of one Sam Waksal, oldest son of Jewish emigrants and Holocaust survivors, a man of irresistible charm, fabulous energy, and great intelligence, a man driven to success and the high life, a man who had bounced around academia without much success until in the 1980s he saw an opportunity to become a player in the cancer game, and, along with his younger brother Harlan, founded ImClone Systems, Inc.It is also about an anticancer drug called Erbitux, originally known as C225 because it was the 225th drug tested by its discoverers, John Mendelsohn and Gordon Sato in 1980. It showed promise because in tests it stopped the growth of tumors in mice.And finally it is a story about how drugs get discovered, how they are developed, and especially how they get approved (or not) by the Food and Drug Administration. And of course it is about the Byzantine and incestuous relationship that exists between that August government agency and the massive pharmaceutical industry.The curious thing about all this is that Imclone never turned a profit, Erbitux never came to market, and most of the people associated with Waksal and ImClone either made out like bandits or got stuck holding the bag.

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